Pleiner lab
Bio-X supports our nanobody research
September, 2024
Our collaboration with the Gao lab at Stanford is supported by a Bio-X Interdisciplinary Initiative seed grant! Excited to get started!
New paper out in Molecular Cell
September 5, 2024
Exciting structural and mechanistic insights into how membrane protein biogenesis factors collaborate to accomodate the enormous diversity of human membrane proteins during their biogenesis at the endoplasmic reticulum membrane. Link here
Tino named 2024 Baxter Faculty Fellow
July 7, 2024
We are extremely grateful to the Donald E. and Delia B. Baxter Foundation for supporting our research into protein homeostasis and its modulation with nanobodies!
The lab is growing!
July 1, 2024
We are excited the Pleiner lab is growing! We welcome Caroline Scheuing as our lab's first graduate student, Maya Biswal as first postdoc, and Kyle Trinh as a MCP rotating student and part of the Stanford Bioscience's ADVANCE Summer Institute program.
Maya
Caroline Scheuing rotates in the lab
Jan 3, 2024
We are welcoming MCP graduate student Caroline Scheuing as rotation student. Very excited to have you on board for the next two months to discover modulatory nanobodies!
Mansi Vasishtha
Feb. 12, 2024
We are excited to have Mansi Vasishtha join the Pleiner lab as a lab manager! We look forward to Mansi contributing her vast experience from managing other labs at Stanford and help out with ongoing projects in the lab as well.
New paper out now in Nature Protocols
Nov 16, 2023
If you are purifying mammalian proteins for structure-function analysis, we got a treat for you! Check out our protease-cleavable anti-GFP & anti-ALFA nanobody-based purification strategy @ Nature Protocols here: https://rdcu.be/drhGs (from Tino's time @VoorheesLab @Caltech)
Mia Greeson rotates in the lab
Oct 3, 2023
We are welcoming MCP graduate student Mia Greeson as our lab's first rotation student. Very excited to have you tackle our first nanobody projects!
Zhiwen (Carmen) Liao joins the lab
Sept 18, 2023
Carmen joins the Pleiner lab part-time to help organize the lab! Her main home base is the Goodman lab. We are very happy she is bringing all her experience to our growing lab!
We made the cover of JCB!
August 07, 2023
Tino's latest postdoc paper from the Voorhees lab at Caltech was chosen to be featured on the cover of the Journal of Cell Biology along with a well-written spotlight article. Artwork by Larissa Ulisko.
Marinda Stanton joins the lab
July 01, 2023
We are excited to have Marinda Stanton join the lab! Marinda will help set-up the lab and work with Tino to get the first projects off the ground.
1st Day at Stanford
June 01, 2023
The lab is finally open! The Pleiner lab received a warm welcome by the Department. We are happy to be here and are looking forward to unboxing all our new toys and setting up the lab! Can't wait to get started with experiments.
New paper published in JCB
May 18, 2023
Part of Tino's postdoctoral work at Caltech just got published. Sorting of membrane proteins to their correct subcellular compartment is an essential process that shapes organelle identity by equipping them with a defined inventory of proteins. We reveal a new mechanism for how selectivity of the insertion machinery at the ER membrane influences the fidelity of sorting ER and mitochondrial membrane proteins.
Time to move
May 04, 2023
Tino's last day at Caltech was an emotional one! So many memories and so much fun. But now it's time to pack up plasmids, cell lines and proteins and move them to Stanford! Very excited to get the lab started!
Preprint alert !
Mar 10, 2023
Our new preprint just dropped on bioRxiv highlighting a powerful strategy to isolate GFP- or ALFA tagged human proteins or protein complexes in high yield and under native conditions for structural and functional analysis using nanobodies!
The Pleiner lab is taking shape
Jan 05, 2023
Lab renovations on the 1st floor of Beckman Center are under way and expected to be completed by end of Feb 2023. The first lab equipment is being purchased and Tino is scouting alpacas to join the lab for first nanobody projects! Exciting times ahead!